. Author manuscript; available in PMC: 2008 Sep 25.

Published in final edited form as: Nat Rev Cancer. 2008 Apr;8(4):299–308. doi: 10.1038/nrc2355

Table 1. Adoptive cell therapy in patients with metastatic melanoma79.

All patients received cyclophosphamide 60 mg/kg for 2 days then fludarabine 25 mg/m² for 5 days. Includes all patients who received expanded tumour-infiltrating lymphocytes (TIL) plus the full preparative regimen as a first TIL treatment. CR, complete response; OR, objective response; PR, partial response; TBI, total body irradiation.

Treatment	Patients (n)	Response (n (%))
		PR	CR	OR
No TBI	43	17 (39.5)	4 (9.3)	21 (48.8)
2 Gy TBI	25	11 (44.0)	2 (8.0)	13 (52.0)
12 Gy TBI	25	14 (56.0)	4 (16.0)	18 (72)