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. 2008 Oct 2;3(10):e3308. doi: 10.1371/journal.pone.0003308

Table 4. Analysis of AEF activity in peripheral blood monocytes isolated from mice with AA amyloid induced by monocytes isolated from mice with AEF-induced AA amyloid.

Donor mice Recipient mice
Mouse Amyloid grade Group No. of mice with amyloid/total no. of mice Amyloid grade
H2-1 1+ J1 2/3 1+–2+
H2-2 3+ J2 3/3 1+
H2-3 2+ J3 2/3 1+
H2-4 1+ J4 3/3 1+–2+
H2-5 2+ J5 2/3 2+

Mice in group J received an i.v. injection of monocytes isolated from H2 (1–5) and a sequential s.c. injection of 0.2 ml 1% silver nitrate day 1, 7 and 14 and were sacrificed day 16.The presence of amyloid was analyzed in spleen after Congo red staining.