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. Author manuscript; available in PMC: 2008 Sep 25.
Published in final edited form as: J Pharmacol Exp Ther. 2007 Nov 30;324(3):1155–1162. doi: 10.1124/jpet.107.130872

Fig. 3.

Fig. 3

State 3 respiration in noninjured and TBHP-injured RPTC supplemented with succinate (10 mM). Succinate was present 0.5 h before, during, and after TBHP exposure. A, complex I-coupled state 3 respiration (state 3 respiration measured using electron donors to complex I of the respiratory chain: 5 mM pyruvate + 5 mM malate). B, complex II-coupled state 3 respiration (state 3 respiration measured using an electron donor to complex II: 10 mM succinate + 0.1 μM rotenone). Results are the average ± S.E.M. of four independent experiments (RPTC isolations). Values with dissimilar superscripts at a given time point are significantly different (P < 0.05) from each other.