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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Bioconjug Chem. 2007 Nov 8;19(1):89–96. doi: 10.1021/bc700161p

Figure 5. Serum stability analysis of 64Cu-labeled M5A conjugates.

Figure 5

64Cu labeled DO3A-VS-M5A was incubated with human serum and analyzed over time by SEC. The major peak at 42 min corresponds to the elution time for IgG. A: SH-DO3A-VS-M5A. B: NH-DO3A-VS-M5A. The sample was also injected into nude mice, blood removed over time, and the serum fraction analyzed by SEC. C: SH-DO3A-VS-M5A. D: NH-DO3A-VS-M5A.