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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Bioconjug Chem. 2007 Nov 8;19(1):89–96. doi: 10.1021/bc700161p

Figure 8. Dynamic biodistribution of 64Cu-labeled hT84.66-M5A MAbs in athymic mice peripherally xenografted with CEA-positive LS-174T colon tumors.

Figure 8

(A) SH-DO3A-VS-M5A; (B) NH-DO3A-VS-M5A. Images are PET anterior-view maximum intensity projections (MIPs) normalized to reflect radiodecay-corrected relative image intensity per unit injected activity. Labels shown in red, yellow and green show directly-measured %ID/g in blood (heart), liver and tumor, respectively. Tumor weights at time of sacrifice were 126 and 155 mg in (A) and (B) respectively.