Table 3. Putative identity, categories of biological function and fold change of a subset of down-regulated genes identified in worms recovered from animals vaccinated with rSm29 associated to adjuvant.
| Contig | Putative identity | Fold Changea Down-regulation with rSm29 plus adjuvant |
| Tegument proteins | ||
| C600716.1 | CD36-like class B scavenger receptor [S. mansoni] | 1.7 |
| C605987.1 | Integral membrane protein/sugar transporter family [B. vulgaris] | 2.1 |
| C601295.1 | Sm23 kDa integral membrane protein [S. mansoni] | 2.0 |
| C607243.1 | Alkaline phosphatase [M. musculus] | 3.1 |
| C610121.1 | Annexin [S. mansoni] | 2.0 |
| Membrane proteins | ||
| C604563.1 | Tetraspanin TE736 [S. japonicum] | 2.1 |
| C609525.1 | Transmembrane protein 49 [X. tropicalis] | 2.6 |
| C605890.1 | ATPase, aminophospholipid transporter [B. Taurus] | 1.9 |
| C606907.1 | Putative insulin receptor [E. multilocularis] | 1.8 |
| C609637.1 | vacuolar proton pump [Danio rerio] | 1.8 |
| C609954.1 | Autocrine motility factor receptor [T. castaneum] | 1.5 |
| C608609.1 | Voltage-dependent anion channel 1 [X. laevis] | 1.6 |
| C601007.1 | UDP dual transporter [C. elegans] | 2.0 |
| C609782.1 | DAD-1-like protein/integral membrane [S. japonicum] | 1.9 |
| Receptors interacting proteins | ||
| C610202.1 | Serine/threonine kinase receptor associated protein [P. troglodytes] | 1.6 |
| C607204.1 | Thyroid receptor interacting protein 13 [H. sapiens] | 1.7 |
| C603157.1 | syndecan binding protein (syntenin) [D. rerio] | 1.5 |
| C606116.1 | G protein beta subunit [P. fucata] | 2.1 |
| C600861.1 | B-cell receptor-associated protein-like protein [S. mansoni] | 1.5 |
| C608810.1 | rhoGAP protein [M. domestica] | 2.7 |
| C714516.1 | TGF-beta receptor interacting protein 1 [C. sinensis] | 1.8 |
| Lipid metabolism | ||
| C601385.1 | SmINSIG [S. mansoni] | 2.3 |
| C601665.1 | Fatty acid-binding protein Sm14 [S. mansoni] | 1.5 |
| C608771.1 | Very low density lipoprotein binding protein [S. japonicum] | 1.8 |
| C711918.1 | Fatty acid coenzyme A ligase 5 [H. sapiens] | 1.7 |
| Other | ||
| C602958.1 | Apoferritin-2 [S. japonicum] | 1.7 |
| C610848.1 | Ferritin heavy chain 2 [S. mansoni] | 2.1 |
| C601146.1 | IB1 protein [S. japonicum] | 2.9 |
| C608351.1 | Tropomyosin [S. mansoni] | 1.7 |
| C600304.1 | src tyrosine kinase [S. mansoni] | 1.7 |
| C603876.1 | PrA2 protein [S. mansoni] | 1.7 |
| C607402.1 | Superoxide dismutase [S. mansoni] | 1.5 |
| C604746.1 | Sm65 antigen [S. mansoni] | 1.5 |
a
statistically significant, q<0.01