Figure 3.

Stiffness changes in response to β-agonist. ASM cells isolated from the relatively hyporesponsive Lewis rat (circles) and the relatively hyperresponsive Fisher rat (squares) were stimulated with increasing doses of ISO (0.01 μM, blue open circles, red open squares; 0.1 μM, teal closed circles, gold closed squares; 1 μM, blue closed circles, red closed squares; 10 μM, purple closed circles, pink closed squares). At each dose of ISO, changes in cell stiffness were normalized to the baseline stiffness of each individual cell before stimulation. For clarity, data are presented at intervals of 3.9 s. Data are presented as mean ± SE (n = 197–346 cells).