Table 6.
Malariometric indexes separated by FcγRIIa R131H genotypes in the Fulani and Dogon ethnic groups.
Dogon | Fulani | |||||||
HH | HR | RR | p-valuea | HH | HR | RR | p-value a | |
Age (mean ± sd) | 15 ± 12 | 16 ± 13 | 20 ± 13 | 15 ± 13 | 23 ± 18 | 20 ± 17 | ||
Spleen rate b (%) | 8 | 13 | 11 | 0.8 | 38 | 36 | 36 | 0.9 |
Hb (mean ± sd) | 13 ± 2 | 12.6 ± 2.4 | 13.3 ± 2.6 | 0.4 | 11 ± 2 | 10.6 ± 2.7 | 10.8 ± 2.3 | 0.9 |
Parasite prevalence c (%) | 67 | 58 | 60 | 0.7 | 49 | 33 | 59 | 0.02 |
Parasite density d (mean ± sd) | 907 ± 4138 | 546 ± 1803 | 243 ± 843 | 0.5 | 330 ± 1138 | 530 ± 2155 | 1533 ± 4734 | 0.2 |
Clones e (mean ± sd) | 4.0 ± 3.7 | 2.9 ± 3.3 | 3.6 ± 3.7 | 0.4 | 1.9 ± 2.6 | 1.3 ± 2.5 | 3.3 ± 3.5 | 0.006 |
HbAS f (%) | 0 | 10 | 6 | 0.2 | 6 | 3 | 18 | 0.01 |
a Differences between the three different genotypes.
b Percentage of individuals with enlarged spleen
c Proportion of infected individuals, measured by PCR
d P. falciparum density (parasites/μl)-mean
e Mean number of clones identified as msp2 alleles, excluding PCR negatives
f Frequency of HbAS carriers detected by PCR.