Table 1.
Summary of the molecular and histological features of the colorectal polyps analyzed
| Molecular Classification | Histological classification | |||||||
| Sample | KRAS | BRAF | PIK3CA | CIMP | MLH1 methylation | Microsatellite instability | Polyp type | Dysplasia |
| 1 | G12D | - | - | Negative | UnMet | MSS | MHA | Mild |
| 2 | G12D | - | - | Negative | nd | MSS | MHA | Mild |
| 3 | G12V | - | - | nd | UnMet | MSS | MHA | Mild |
| 4 | G12V | - | - | Negative | nd | MSS | HP | - |
| 5 | G13D | - | - | Negative | nd | MSS | HP | - |
| 6 | G13D | - | - | Negative | nd | MSS | MHA | Mild |
| 7 | - | V600E | - | Positive | UnMet | MSS | SA | Mild |
| 8 | - | V600E | - | Positive | UnMet | MSS | SA | Mild |
| 9 | - | V600E | - | Positive | nd | MSS | SA | Mild |
| 10 | - | V600E | - | Negative | nd | MSS | SA | Mild |
| 11 | - | V600E | - | nd | nd | MSS | SA | Moderate |
| 12 | - | - | R1023Q | nd | nd | MSS | MHA | Mild |
| 13 | - | - | - | Negative | UnMet | MSS | MHA | Mild |
| 14 | - | - | - | Negative | UnMet | MSS | HP | - |
| 15 | - | - | - | Negative | UnMet | MSS | MHA | Mild |
| 16 | - | - | - | nd | nd | MSS | MHA | Mild |
| 17 | - | - | - | nd | nd | MSS | HP | - |
UnMet – unmethylated; nd – not determined; MHA – Mixed hyperplastic and adenomatous; HP – Hyperplastic polyp; SA – Serrated adenoma