Table 3.
∊ | GRR=1.4 |
GRR=1.6 |
GRR=1.8 |
GRR=2.0 |
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---|---|---|---|---|---|---|---|---|---|---|---|---|
χ2 | P | U | χ2 | P | U | χ2 | P | U | χ2 | P | U | |
500 case and 500 control individuals | ||||||||||||
10 | 38 | 23 | 19 | 44 | 41 | 33 | 41 | 47 | 45 | 42 | 51 | 45 |
20 | 50 | 47 | 42 | 64 | 62 | 57 | 61 | 70 | 64 | 62 | 72 | 69 |
30 | 59 | 64 | 54 | 77 | 69 | 68 | 69 | 82 | 79 | 73 | 82 | 84 |
40 | 69 | 71 | 69 | 82 | 79 | 80 | 77 | 86 | 86 | 80 | 88 | 91 |
50 | 78 | 81 | 82 | 89 | 85 | 85 | 81 | 89 | 91 | 85 | 91 | 93 |
60 | 85 | 86 | 86 | 90 | 88 | 89 | 88 | 94 | 93 | 94 | 94 | 97 |
70 | 92 | 92 | 90 | 94 | 92 | 94 | 93 | 95 | 94 | 97 | 96 | 98 |
80 | 98 | 96 | 97 | 98 | 97 | 99 | 98 | 97 | 97 | 99 | 97 | 99 |
2000 case and 2000 control individuals | ||||||||||||
10 | 44 | 48 | 45 | 44 | 52 | 52 | 49 | 65 | 68 | 57 | 72 | 74 |
20 | 68 | 63 | 66 | 62 | 72 | 69 | 72 | 78 | 79 | 77 | 88 | 88 |
30 | 76 | 81 | 80 | 74 | 88 | 82 | 79 | 88 | 88 | 89 | 95 | 94 |
40 | 84 | 87 | 90 | 84 | 92 | 87 | 86 | 92 | 89 | 95 | 96 | 97 |
50 | 88 | 93 | 97 | 94 | 96 | 91 | 91 | 94 | 92 | 96 | 98 | 99 |
60 | 95 | 97 | 98 | 97 | 99 | 96 | 95 | 98 | 97 | 97 | 99 | 100 |
Based on 100 simulated datasets for each setting, with 5% WR and ρ=40. Columns denoted χ2 correspond to single-marker χ2-test results, while columns denoted ‘P’ (‘U’, respectively) correspond to Blossoc results using m=5 for phased (unphased, respectively) data.