Table 1.

Characteristics of the risk prediction methods studied in this work

	Genotype	Dim. reduction	Structure	Learning algo.	Phenotype
1	AURKA
2	BD		COMBUNIV	WILCOXON	HG
3	BD		COMBUNIV	COX	SURV
4	BD		MULTIV	LM	TOE
5	BD		MULTIV	COX	SURV
6	GW	RANK (CV)	COMBUNIV	WILCOXON	HG
7	GW	RANK (CV)	COMBUNIV	COX	SURV
8	GW	RANK (CV)	MULTIV	RCOX	SURV
9	GW	PCA (CV)	COMBUNIV	WILCOXON	HG
10	GW	PCA (CV)	COMBUNIV	COX	SURV
11	GW	PCA (CV)	MULTIV	RCOX	SURV
12				GENE76
13				GGI

We will use the words in bold to refer to the models that were fully defined in previous publications. Otherwise, the model name is a concatenation of all its characteristics separated by ‘.’.