Table 2. Impact of ivermectin treatment on STH infections in 3,705 school-age children.
No-Treatment | Ivermectin | Total | Univariate analysis | Multivariate analysis | |||
1953 | 1752 | 3705 | Odds ratio | p | Odds ratio* | p | |
(95% CI) | (95% CI) | ||||||
STH infections | |||||||
Any helminth | |||||||
Negative | 267 (13.7) | 652 (37.2) | 919 (24.8) | 1.0 | 1.0 | ||
Positive | 1686 (86.3) | 1100 (62.8) | 2786 (75.2) | 0.24 (0.12–0.45) | <0.001 | 0.27 (0.15–0.47) | <0.001 |
A. lumbricoides | |||||||
Negative | 834 (42.7) | 895 (51.1) | 1729 (46.7) | 1.0 | 1.0 | ||
Positive | 1119 (57.3) | 857 (48.9) | 1976 (53.3) | 0.81 (0.42–1.53) | 0.512 | 0.96 (0.45–2.05) | 0.916 |
T. trichiura | |||||||
Negative | 362 (18.5) | 1208 (68.9) | 1570 (42.4) | 1.0 | 1.0 | ||
Positive | 1591 (81.5) | 544 (31.1) | 2135 (57.6) | 0.09 (0.04–0.18) | <0.001 | 0.06 (0.03–0.14) | <0.001 |
Hookworm | |||||||
Negative | 1877 (96.1) | 1492 (85.1) | 3369 (90.9) | 1.0 | 1.0 | ||
Positive | 76 (3.9) | 260 (14.8) | 336 (9.1) | 5.71 (2.26–14.43) | <0.001 | 5.53 (1.81–16.86) | 0.003 |
S. stercoralis | |||||||
Negative | 1939 (99.3) | 1750 (99.9) | 3689 (99.6) | … | … | ||
Positive | 14 (0.7) | 2 (0.1) | 16 (0.4) | ** | ** |
*: ORs adjusted for age, sex, maternal educational level, monthly income, household electric appliances, crowding, bathroom, water source and number of ivermectin treatments received.
**: Cannot be reliably estimated because of small numbers.