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. 2008 Sep 10;2(9):e293. doi: 10.1371/journal.pntd.0000293

Table 2. Impact of ivermectin treatment on STH infections in 3,705 school-age children.

No-Treatment Ivermectin Total Univariate analysis Multivariate analysis
1953 1752 3705 Odds ratio p Odds ratio* p
(95% CI) (95% CI)
STH infections
Any helminth
Negative 267 (13.7) 652 (37.2) 919 (24.8) 1.0 1.0
Positive 1686 (86.3) 1100 (62.8) 2786 (75.2) 0.24 (0.12–0.45) <0.001 0.27 (0.15–0.47) <0.001
A. lumbricoides
Negative 834 (42.7) 895 (51.1) 1729 (46.7) 1.0 1.0
Positive 1119 (57.3) 857 (48.9) 1976 (53.3) 0.81 (0.42–1.53) 0.512 0.96 (0.45–2.05) 0.916
T. trichiura
Negative 362 (18.5) 1208 (68.9) 1570 (42.4) 1.0 1.0
Positive 1591 (81.5) 544 (31.1) 2135 (57.6) 0.09 (0.04–0.18) <0.001 0.06 (0.03–0.14) <0.001
Hookworm
Negative 1877 (96.1) 1492 (85.1) 3369 (90.9) 1.0 1.0
Positive 76 (3.9) 260 (14.8) 336 (9.1) 5.71 (2.26–14.43) <0.001 5.53 (1.81–16.86) 0.003
S. stercoralis
Negative 1939 (99.3) 1750 (99.9) 3689 (99.6)
Positive 14 (0.7) 2 (0.1) 16 (0.4) ** **

*: ORs adjusted for age, sex, maternal educational level, monthly income, household electric appliances, crowding, bathroom, water source and number of ivermectin treatments received.

**: Cannot be reliably estimated because of small numbers.