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. 2008 Sep 10;2(9):e293. doi: 10.1371/journal.pntd.0000293

Table 4. Impact of ivermectin treatment on STH infections in 1,701 pre-school children.

No-Treatment Ivermectin Univariate analysis Multivariate analysis
n = 925 n = 776 Odds ratio p Odds ratio* p
(95% CI) (95% CI)
STH infections
Any helminth,
Negative 326 (35.2) 460 (59.3) 1.0 1.0
Positive 599 (64.8) 316 (40.7) 0.33 (0.22–0.50) <0.001 0.34 (0.21–0.56) <0.001
A. lumbricoides
Negative 570 (61.6) 519 (66.9) 1.0 1.0
Positive 355 (38.4) 257 (33.1) 0.64 (0.38–1.09) 0.102 0.67 (0.38–1.19) 0.174
T. trichiura
Negative 413 (44.6) 654 (84.3) 1.0 1.0
Positive 512 (55.4) 122 (15.7) 0.12 (0.08–0.20) <0.001 0.12 (0.07–0.21) <0.001
Hookworm
Negative 920 (99.5) 768 (99.0)
Positive 5 (0.5) 8 (1.0) ** **
S. stercoralis
Negative 904 (97.7) 775 (99.9) ….
Positive 21 (2.3) 1 (0.1) ** **

*: Odds ratio adjusted by age, sex and ivermectin treatment.

**: Cannot be reliably estimated because of small numbers.