Table 4. Impact of ivermectin treatment on STH infections in 1,701 pre-school children.
No-Treatment | Ivermectin | Univariate analysis | Multivariate analysis | |||
n = 925 | n = 776 | Odds ratio | p | Odds ratio* | p | |
(95% CI) | (95% CI) | |||||
STH infections | ||||||
Any helminth, | ||||||
Negative | 326 (35.2) | 460 (59.3) | 1.0 | 1.0 | ||
Positive | 599 (64.8) | 316 (40.7) | 0.33 (0.22–0.50) | <0.001 | 0.34 (0.21–0.56) | <0.001 |
A. lumbricoides | ||||||
Negative | 570 (61.6) | 519 (66.9) | 1.0 | 1.0 | ||
Positive | 355 (38.4) | 257 (33.1) | 0.64 (0.38–1.09) | 0.102 | 0.67 (0.38–1.19) | 0.174 |
T. trichiura | ||||||
Negative | 413 (44.6) | 654 (84.3) | 1.0 | 1.0 | ||
Positive | 512 (55.4) | 122 (15.7) | 0.12 (0.08–0.20) | <0.001 | 0.12 (0.07–0.21) | <0.001 |
Hookworm | ||||||
Negative | 920 (99.5) | 768 (99.0) | – | … | … | … |
Positive | 5 (0.5) | 8 (1.0) | ** | ** | ||
S. stercoralis | ||||||
Negative | 904 (97.7) | 775 (99.9) | … | … | …. | … |
Positive | 21 (2.3) | 1 (0.1) | ** | ** |
*: Odds ratio adjusted by age, sex and ivermectin treatment.
**: Cannot be reliably estimated because of small numbers.