Table 1.
Clinical features of patients
| Case | Sex | Agea | Ethnicity | Diagnosis | Onset Months | Regression | Language | ADI-R criteria | CARS | Cognitive levelb | Seizures |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | f | 7.0 | Caucasian | autism | 30 | Yes (at 30 months) | non verbal | Yes | 36.5 | severe mental retardation | – |
| 2 | m | 10.4 | Caucasian | autism | 24 | No | non verbal | Yes | 44 | severe mental retardation | – |
| 3 | m | 13.6 | Caucasian | autism | 35 | Yes (at 35 months) | non verbal | Yes | 37 | mild mental retardation | – |
| 4 | f | 6.9 | Caucasian | autism | 15 | No | delayed (first phrases 60 months) | Yes | 43 | borderline intellectual functioning | – |
| 5 | m | 10.5 | Caucasian | autism | 15 | No | delayed (first words 25 months, phrases 37 months) | Yes | 34 | borderline intellectual functioning | – |
| 6 | m | 4.0 | Caucasian | autism | 19 | No | non verbal | Yes | 44.5 | mild mental retardation | – |
ADI-R, Autism Diagnostic Interview-Revised [15]; CARS, Childhood Autism Rating Scale [42] (scores between 30 and 36.5 indicate mild to moderate autism while scores greater than 36.5 reflect severe autism).
a
Age in years at which individual was evaluated for inclusion in the study.
b
Assessed using age and developmentally appropriate instruments, including the Psychoeducational Profile, the Wechsler Intelligence Scale for Children-Revised, and the Leiter.