Table III.
Possible functions of genes in the vicinity of LpxE based on similarities to selected gene products
Predicted protein (length) | Related protein with characterized function if any (length) | Accession number | Homologya | E value |
---|---|---|---|---|
Orf1 (628) | Integral inner membrane metabolite transport protein, MtbA, Bradyrhizobium japonicum (555) | AAF78796 | 254/301/343 | 10−132 |
LpxE (244) | Putative phosphatidic acid phosphatase, Lactococcus lactis (218) | AAC45388 | 43/56/125 | 0.001 |
Orf3 (370) | β-Isopropylmalate dehydrogenase, LeuB, A. tumefaciens (370) | AAA22089 | 326/344/370 | 10−175 |
Orf4 (313) | L-Serine dehydratase, SdhL, Rattus norvegicus (327) | CAA68721 | 144/196/313 | 10−57 |
Orf5 (201) | 3-Isopropylmalate dehydratase small subunit, LeuD, Azotobacter vinelandii (215) | CAA722150 | 107/135/201 | 2 × 10−53 |
Homology is given as the number of identities/number of positives/number of residues (including gaps) in the related segment. The gapped Blastp algorithm (86) was used to identify possible orthologs using the predicted R. leguminosarum proteins as the probe.