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Transepithelial permeability of biotin-saquinavir in different cell lines
| P appA-B (cm/sec, ×10−7) | P appB-A (cm/sec, ×10−7) | Efflux Index | |
|---|---|---|---|
| MDCK-MDR1 | 4.61 (± 0.50) | 8.38 (± 0.31) | 1.82 |
| MDCK-WT | 5.23 (± 0.61) | N/D | |
| Caco-2 | 3.90 (± 0.36) | 10.68 (± 0.59) | 2.74 |
