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Topologies give rise to radically different structural appearance. Structures and electrostatic potential colored surfaces of the parallel (top), ‘basket’ lateral, diagonal, lateral loop (middle) and the all double chain reversal (bottom) topologies. The electrostatic surfaces are colored red (−10 kT/e) to blue (10 kT/e) and the bases are guanine in green, thymine in blue, and adenine in red.
