Figure 10.

A549 cells migrate equally on LAP and FN. (A) Cell motility assays were performed in Boyden chambers as described in MATERIALS AND METHODS. The results indicate the number of cells that migrated from the top to the bottom of a porous filter that was coated on the bottom or on both sides with a test protein. (B) Cells were allowed to migrate on LAP as in A for 16 h, in the presence or absence of mAbs to αv (50% L230 hybridoma medium), β1 (10 μg/ml 4B4), or αvβ5 (1:500 dilution of P1F6 ascites fluid).