Table 1.

Comparison of different expansion protocols for human UCB hematopoietic stem cells using various cytokine combinations

Cytokine cocktail	Serum	Expansion of CD34+ cells at day 7 (fold)	Reference
SCF, GM-CSF, IL-3, TPO, Flt-3L	20% FBS	11.21 ± 9.27	Mohamed et al. (2006)
SCF, GM-CSF, IL-3, TPO	20% FBS	10.18 ± 8.64	Mohamed et al. (2006)
SCF, GM-CSF, IL-3, TPO, IL-6	20% FBS	9.87 ± 8.57	Mohamed et al. (2006)
SCF, Flt-3L, TPO, IL-3, IL-6	20% FBS	3.2	Yang et al. (2008)
SCF, IL-6, IL-3	20% FBS	2.44	Qunliang et al. (2006)
SCF, TPO, Flt-3L, IL-3, G-CSF, IL-6	0%	27	Yao et al. (2006)
SCF, GM-CSF, IL-3, TPO, Flt-3L	0%	25.11 ± 13.50	Mohamed et al. (2006)
SCF, GM-CSF, IL-3, TPO	0%	24.98 ± 13.66	Mohamed et al. (2006)
SCF, GM-CSF, IL-3, TPO, IL-6	0%	24.56 ± 13.37	Mohamed et al. (2006)
G-CSF, IL-6, EPO	0%	6.36 ± 0.33	Chivu et al. (2004)

FBS: Fetal bovine serum