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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: Cancer Res. 2008 Jul 15;68(14):5778–5784. doi: 10.1158/0008-5472.CAN-07-6441

Figure 5. Survivin induced killing of CD133+ cells in vitro in response to radiation.

Figure 5

(A) CD133+ enriched tumor cells were infected with either AdWT or CRAd-S-pk7, 24h prior to exposure to radiation (2Gy) followed by 24 hour growth in complete media. Cytotoxicity was measured by LDH assay. (Mean ± SD is presented, * p<0.05) Experiments were performed twice with 6 replicates per condition. (B) Viral replication was determined via E1A copy number measurement using qPCR and presented as copies per ng total DNA. Experiments were performed twice in triplicates.