Figure 2.

Thrombin-induced rounding of endothelial cells is preceded by stress fiber formation. Confluent EA.hy926 monolayers were stained with FITC-phalloidin after treatment with medium alone (A), 10 nM thrombin for 2 min (B) or 10 nM thrombin for 15 min (C). Photographs (magnification, 1000×) are representative of three different experiments. Arrow indicates cell surface blebbing.