Bhat et al. 1999 |
Binary |
0 = absence of allele |
Binary |
1/0/0 = unaffected |
1 |
15 |
|
|
1 = presence of allele |
|
0/1/0 = mildly affected |
|
|
|
|
|
|
0/0/1 = severely affected |
|
|
Bush et al 2005 |
Discrete |
-1, -1 = 1/1 genotype |
Binary |
0 = unaffected |
GP evolved |
|
|
0, + 2 = 1/2 genotype |
|
1 = affected |
|
|
|
|
+1, -1 = 2/2 genotype |
|
|
|
|
Costello et al. 2003 |
Dicrete |
Varied |
Binary |
0 = unaffected |
Multiple variations |
|
|
|
|
1 = affected |
|
|
Curtis et al. 2001 |
Discrete |
0 = AA genotype |
Binary |
0 = unaffected |
2 |
3 |
|
|
1 = AB genotype |
|
1 = affected |
|
|
|
|
2 = BB genotype |
|
|
|
|
Curtis 2007 |
Discrete |
0 = AA genotype |
Binary |
0 = unaffected |
2 |
3 |
|
|
1 = AB genotype |
|
1 = affected |
|
|
|
|
2 = BB genotype |
|
|
|
|
Giachino et al 2007 |
Discrete and Continuous |
Categorical values of genotypes and clinical features |
Binary |
0 = unaffected |
1 |
unknown |
|
|
|
|
1 = affected |
|
|
Li et al. 1999 |
Discrete |
IBD sharing |
Binary |
0/1 = concordant or not |
Multiple variations |
|
|
+1= shared allele |
|
0/1 = affected or unaffected |
|
|
|
|
-1 = unshared allele |
|
|
|
|
|
|
0 = uninformative |
|
|
|
|
Lin et al 2006 |
Discrete |
Categories of genotype combinations |
Binary |
0 = non-response |
Multiple variations |
|
|
|
|
1 = response |
|
|
Lucek and Ott 1997 |
Binary |
0 = absence of allele |
Binary |
4 nodes for each trait (20 total nodes) |
1 |
70 |
|
|
1 = presence of allele |
|
0 = quantitative trait off |
|
|
|
|
|
|
1 = quantitative trait on |
|
|
Lucek et al. 1998 |
Discrete |
IBD sharing |
Binary |
+1,+1 = target output |
1 |
√220 |
|
|
+1= shared allele |
|
0, +1 = noise |
|
|
|
|
-1 = unshared allele |
|
|
|
|
|
|
0 = uninformative |
|
|
|
|
Marinov and Weeks 2001 |
Discrete |
IBD sharing |
Binary |
+1,+1 = target output |
1 |
√220 |
|
|
+1= shared allele |
|
0, +1 = noise |
|
|
|
|
-1 = unshared allele |
|
|
|
|
|
|
0 = uninformative |
|
|
|
|
Matchenko-Shimko and Dube 2006 |
Discrete |
Three combinations of possible allele combinations, transformed to a 0–1 range |
Binary |
0 = control |
Multiple variations |
|
|
|
|
1 = case |
|
|
Motsinger et al (2006a) |
Discrete |
-1, -1 = 1/1 genotype |
Binary |
0 = unaffected |
GP Evolved |
|
|
0, + 2 = 1/2 genotype |
|
1 = affected |
|
|
|
|
+1, -1 = 2/2 genotype |
|
|
|
|
Motsinger et al (2006b) |
Discrete |
-1, -1 = 1/1 genotype |
Binary |
0 = unaffected |
GE Evolved |
|
|
0, + 2 = 1/2 genotype |
|
1 = affected |
|
|
|
|
+1, -1 = 2/2 genotype |
|
|
|
|
North et al 2003 |
Discrete |
0 = AA genotype |
Binary |
0 = unaffected |
Multiple Variations |
|
|
1 = AB genotype |
|
1 = affected |
|
|
|
|
2 = BB genotype |
|
|
|
|
Ott 2001 |
Discrete |
-1, -1 = 1/1 genotype |
Binary |
0 = unaffected |
NA |
|
|
0, +2 = 1/2 genotype |
|
1 = affected |
|
|
|
|
+1, -1 = 2/2 genotype |
|
|
|
|
Pankratz et al. 2001 |
Discrete |
IBD sharing |
Binary |
1/1 = affected/affected |
1 |
4 |
|
|
+1 = shared allele |
|
0/1 = affected/unaffected |
|
|
|
|
-1 = unshared allele |
|
|
|
|
|
|
0 = uninformative |
|
|
|
|
Penco et al 2005 |
Discrete |
Categories of allele combinations at each genotype |
Binary |
0 = unaffected |
Multiple variations, including and evolutionary process |
|
|
|
|
1 = affected |
|
|
Pociot et al. 2004 |
Discrete |
Number of categories per sliding window |
Binary |
0 = unaffected |
Multiple variations |
|
|
|
|
1 = affected |
|
|
Ritchie et al. 2003 |
Discrete |
-1, -1 = 1/1 genotype |
Binary |
0 = unaffected |
GP evolved |
|
|
0, + 2 = 1/2 genotype |
|
1 = affected |
|
|
|
|
+1, -1 = 2/2 genotype |
|
|
|
|
Saccone et al. 1999 |
Discrete |
IBD sharing |
Binary |
1/1 = affected/affected |
18 variations |
|
|
+1= shared allele |
|
0/1 = affected/unaffected |
|
|
|
|
-1 = unshared allele |
|
|
|
|
|
|
0 = uninformative |
|
|
|
|
Serretti and Smeraldi 2004 |
Discrete |
SERPR*l/l = 1 |
Binary |
0 = nonresponse |
1 |
7 |
|
|
SERPR*l/s = 2 |
|
1 = response |
|
|
|
|
SERPR*s/s = 2 |
|
|
|
|
|
|
TPH*C/C = 1 |
|
|
|
|
|
|
TPH*C/A = 2 |
|
|
|
|
|
|
TPH*A/A = 2 |
|
|
|
|
Shoemaker et al. 2001 |
Varied |
Varied |
Binary |
0 = unaffected |
1 |
unknown |
|
|
|
|
1 = affected |
|
|
Tomita et al 2004 |
Discrete |
Homozygous for major allele = (0.1, 0.1) |
Binary |
0.9 = case |
Multiple variations |
|
|
Heterozygous = (0.1, 0.9) |
|
0.1 = control |
|
|
|
|
Homozygous for minor allele = (0.9, 0.9) |
|
|
|
|
Zandi et al. 2001 |
Contin. |
Pedigree-specific NPL scores |
Binary |
1,1 = case pedigree |
15 variations |
|
|
|
|
1,0 = control pedigree |
|
|