Table 2.
Inclusion and exclusion criteria
| Inclusion criteria | 
| • study includes children age 0 – 18 inclusive; and | 
| • study investigates manipulation in a therapeutic clinical context; and | 
| • study was published in a peer reviewed publication, or was reported at Conference Proceedings; or | 
| • relevant systematic review. | 
| Exclusion criteria | 
| • descriptive studies (ie surveys) that do not investigate manipulation in a therapeutic clinical context, | 
| • studies in which a small number of pediatric subjects were a part of a larger adult trial, and the results are not reported separately, | 
| • abstracts from conference proceedings which were later published in the scholarly literature. |