Fig. 3.

Brain regions differentially activated in children and adults across all irony tasks. (A). Children showed significantly greater activity than adults in the MPFC (x = −8, y = 58, z = 20; P < 0.05), the left inferior frontal gyrus (x = −48, y = 16, z = 14; P = 0.05) and the right posterior STS (x = 42, y = −44, z = 16; P < 0.05). (B) Adults showed reliably greater activity than children in posterior temporal-occipital regions, including the left amygdala (x = −22, y = −2, z = −12; P < 0.05, SVC), bilateral FG (L: x = −28, y = −64, z = −8; R: x = 30, y = −66, z = −14; P < 0.05) and left STG (x = −36, y = −26, z = 8; P < 0.05). All regions shown survive a threshold of t > 1.80 and whole-volume correction for multiple comparisons at the cluster level, P < 0.05, or small volume correction (SVC) where noted.