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. 2008 Oct;19(10):4393–4403. doi: 10.1091/mbc.E07-09-0946

Figure 6.

Figure 6.

Mnl1-dependent gene activation occurs in stressed but not dying C. albicans cells. (A) Mean fold change in transcript levels for the subset of 114 Mnl1-dependent genes in wild-type C. albicans after exposure to 20, 120, or 300 mM acetic acid in SC-pH 3.0 for 0–300 min. (B) We have identified proteins corresponding to 13 Mnl1-dependent genes on 2D gels. The mean fold change in the levels of these proteins in wild-type C. albicans cells after exposure to 20, 120, or 300 mM acetic acid in SC-pH 3.0 for 0–300 min are presented. (C) Changes in levels of Acs1, Cta1, Hsp60, Psa1, Ttr1, Cdc12, Ssb1, and Ssc1 proteins are apparent in weak acid stress–treated (20 mM acetic acid) cells, but not in dying cells exposed to 120 or 300 mM acetic acid for 1 h. A full list of proteome changes associated with these treatment conditions is provided in the Supplementary Material (Sup3.xls) along with a reference 2D gel map.