Table 1.

HER genes

Gene	ORF	Protein description
Class I: no structures
BNI1	YNL271C	Formin, involved in budding and actin dynamics
BNR1	YIL159W	Formin, involved in budding and actin dynamics
HER2	YMR293C	Verified ORF of unknown function
VMA2	YBR127C	Subunit B of V-ATPase, proton pump found throughout endomembrane system
Class II: only nuclear structures
ERG28	YER044C	ER membrane protein, facilitates protein–protein interactions
ERV25	YML012W	Member of p24 family, involved in ER-to-Golgi transport
HER1	YOR227W	Verified ORF of unknown function
HOF1	YMR032W	Protein with SH3 domain, involved in cytokinesis and cytoskeletal dynamics
COD1/SPF1	YEL031W	ER localized P-type ATPase
Class III: nuclear structures/altered cytoplasmic (non-nuclear) ER
PSD1	YNL169C	Mitochondrial phosphatidyl serine decarboxylase, PC biosynthesis
CHO2	YGR157W	PE methyltransferase (PEMT), PC biosynthesis
OPI3	YJR073C	Phospholipid methyltransferase, PC biosynthesis
Class IV: general ER defect
NEM1	YHR004C	Controls nuclear growth, negative regulator of phospholipid biosynthetic genes
SPO7	YAL009W	Controls nuclear growth, negative regulator of phospholipid biosynthetic genes