Table 1.
Overview of the experimental transmission studies
Number of contact birdsb | |||||
---|---|---|---|---|---|
Experiment | Vaccine | Virus | HI titrea (log2) | Infected | Dead |
1 | La Sota | NL93 | 0 to 2 | 9, 10 | 0, 1 |
2 | La Sota | Herts33/56 | 0 to 2 | 5 | 0 |
3 | La Sota | California71 | 0 to 2 | 10 | 1 |
4 | Ulster | NL93 | 0 to 2 | 10, 10 | 4, 4 |
5 | La Sota | NL93 | ≥3 | 0, 4, 10 | 0, 0, 0 |
6 | La Sota | Herts33/56 | ≥3 | 0, 2 | 0, 0 |
7 | La Sota | California71 | ≥3 | 1, 3 | 0, 1 |
8 | Ulster | NL93 | ≥3 | 7 | 0 |
Experiments 2, 3, and 8 consist of one trial, Experiments 1, 4, 6, and 7 contain two trials, and Experiment 5 contains three trials. Each trial initially contained 10 infected birds and 10 uninfected contact birds. The vaccines are based on the La Sota (Nobilis Clone30) and Ulster (NDW Poulvac) viruses. The challenge viruses are NL93 (APMV-1/chicken/Netherlands/152608/93), Herts33/56, and California71.
Range of HI titres of the birds just before the start of the experiment.
Number of contact birds that were infected or died per trial.