Figure 5.

The crb gene is regulated by Stat through 4n sites. (A) Schematic representation of the crb gene showing the localization in the spiracle enhancer of the putative Stat-binding sites analysed (red asterisks (4n sites), black asterisk (3n site)). (B) Expression of the spiracle enhancer in the wild type. (C) Expression in the triple 3n4n4n mutant (- - -). (D) Expression in the 3n mutant site (-4n4n). (E) Expression in the double 4n4n mutant sites (3n- -). Stat, signal transducer and activator of transcription.