Table 2.
Findings of linkage analysis.
Analysis Method |
Whole data (ASPs = 190) |
Subset Data (Positive LOD score families) (ASPs = 77) | ||
Sac1 LOD score (P value) |
-75G>A | +83C>T | ||
Multipoint Linkage analysis | NS | 7.42 (<0.001) | ||
Single Point Linkage | NS | 4.49 (<0.0001) | 2.77 (0.0002) | NS |
IBD Pi (P value) |
NS | Pi 0.59 (<0.0001) | Pi 0.56 (<0.0001) | Pi 0.52 (0.0012) |
QTL | NS | TC 1.42 (0.005) HDL-c 1.72 (0.002) ApoB 1.19 (0.010) |
NS | NS |
ASPs, Affected sib pairs; IBD, identity by descent; Pi, mean proportion of allele sharing; NS, Not significant, QTL, Quantitative trait loci.