Figure 2.
Effect of targeted inhibition of LEK1 expression on DC expression of cytokines. WT DC and LEK1 knockdown DC were pulsed with MoPn (MOI 1:5) for 1 h and the supernatants were analyzed for cytokines expression (indicated in the figure), using Luminex technology, as described in the Materials and Methods section. Results represent the means of 3 independent experiments. The control oligomer with a scrambled sequence, as described in the Materials and Methods section, did not show any detectable biological activity.