Fig. 1.

Galectin-1 immunostaining and LGALS1 expression in normal-term placenta and extraembryonic membranes. (A) Galectin-1 expression, shown with shades of brown, is strong in the placenta (p) and fetal membranes (fm), and the most intense in maternal decidua (de). (B) All layers of the fetal membranes [amnion (am); chorioamniotic mesenchyma (cm); chorion (ch)] stained for galectin-1; maternal decidua (de) is the richest source of galectin-1. (C) All placental cell types (trophoblasts [tr], stromal cells [sc], villous endothelium [en]) stained for galectin-1. Immunohistochemistry, hematoxylin counterstain, magnification ×200 (B) and ×400 (C). (D) LGALS1 expression was 3.6-fold higher in the membranes including maternal decidua (n = 6) than in placentas (n = 6) of the same patients. Boxes represent medians and interquartile ranges, whereas whiskers represent the most extreme data points.