Table 1. Annotation of alternative cassette exons bound by SF2/ASF.
Partial list of alternative cassette exons bound by SF2/ASF | |||||
Gene ID | Exon Position | Gene Description | Localization | Gene Family | Function |
ACIN1 | 12 | apoptotic chromatin condensation inducer 1 | Nucleus | enzyme | apoptotic chromosome condensation |
BECN1 | 11 | beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) | Nucleus; Polysome | other | anti-apoptosis;cellular defense response |
CALM2 | 4 | calmodulin 2 (phosphorylase kinase, delta) | Cytoplasm | other | Calcium Binding;G-protein coupled receptor protein signaling pathway |
DHX15 | 5 | DEAH (Asp-Glu-Ala-His) box polypeptide 15 | Cytoplasm | enzyme | mRNA processing |
ERCC6 | 2 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | Cytoplasm | transcription regulator | transcription-coupled nucleotide-excision repair |
MAPK3 | 6 | mitogen-activated protein kinase 3 | Cytoplasm | kinase | intracellular signaling cascade |
NUP43 | 4 | nucleoporin 43kDa | Nucleus; Cytoplasm; Polysome | transporter | nuclear envelope |
PIP5K2A | 7 | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | Nucleus | kinase | glycerophospholipid metabolic process |
SON | 3 | SON DNA binding protein | Nucleus | other | anti-apoptosis |
TCF12 | 9 | transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) | Cytoplasm | transcription regulator | regulation of transcription from RNA polymerase II promoter |
WDR42A | 11 | WD repeat domain 42A | Nucleus; Cytoplasm | other | Unknown |
Y13871 | 1 | hypothetical protein LOC202181 | Nucleus; Cytoplasm; Polysome | other | Unknown |
ZHX1 | 3 | zinc fingers and homeoboxes 1 | Nucleus | transcription regulator | negative regulation of transcription, DNA-dependent |
Exons were annotated manually according to AceView and FAST-DB databases. Column Headers: Gene ID, official gene symbol; Exon position, number of exon within the primary transcript; Gene Description; Localization, the sub-cellular fraction used for CLIP experiment; Gene Family; Function, the primary encoded function of gene. This table is a partial list of cassette exons bound by SF2/ASF. The complete list can be found in Table S1.