|
6.6 million newborns |
1.4 million cases of hydrocele |
3.2 million DALYs |
|
|
800,000 cases of lymphedema |
2.8 million DALYs |
|
|
4.4 million cases of subclinical disease |
? |
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Assumptions and Reasoning
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1) 66 million babies born into at-risk areas under MDA 2000–2007 (discounted for infant mortality) [11]
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2) LF infections occur in 10% of at-risk population [3]
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3) 12.5% of LF infections result in lymphedema, 20.8% in hydrocele, 66.7% in subclinical damage [3]
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4) Disability weights (based on Global Burden of Disease methods): 0.105 for lymphedema, 0.073 for hydrocele; onset at age 20; life span is Region-specific |
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5) LF transmission (estimated by mosquito infection rates) falls progressively to 50%, 25%, 12%, 6%, and 0% pre-MDA levels after each of the first 5 MDAs, respectively |
