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. 2008 Jun 19;178(7):667–672. doi: 10.1164/rccm.200802-309OC

TABLE 3.

RELATIVE CONTRIBUTION OF RHINOVIRUS WHEEZING ILLNESSES AND AEROALLERGEN SENSITIZATION TO RISK OF ASTHMA AT AGE 6 YEARS

OR (95% CI)
RV Wheezing Aeroallergen Sensitization Asthma
RV Wheezing Aeroallergen Sensitization
n n %
First year of life
 No No 183 38 21 2.8 (1.4, 5.6) 3.6 (1.7, 7.7)
 No Yes 27 12 45
 Yes No 38 15 39
 Yes Yes 7 6 86
Third year of life
 No No 150 21 14 25.6 (8.2, 79.6) 3.4 (1.7, 6.9)
 No Yes 50 18 36
 Yes No 16 13 81
 Yes Yes 14 13 93

Definition of abbreviations: CI = confidence interval; OR = odds ratio; RV = rhinovirus.

Aeroallergen sensitization was determined by RAST in the first and third year of life. ORs for Year 6 asthma were determined by logistic regression analyses. Aeroallergen sensitization did not modify the effects of RV wheezing on subsequent asthma risk (interaction P value, 0.61 and 0.99, in the 1st and 3rd yr of life, respectively).