Fig. 5.

Density of CGRP- and SP-immunopositive nerve fibers in the ventral and dorsal dura of controls (group 1), laminectomized rats (group 2), and animals that underwent laminectomy and application of free autologous fat grafts (group 3). At 6 weeks post surgery the density of CGRP-ir fibers increased significantly above control in the dorsal and ventral dura of the laminectomized animals. The application of fat grafts could not prevent the increase in the density of stained nerve fibers. For C GRP-ir comparisons were carried out with Student’s unpaired t test; n = 4. *P < 0.05, **P < 0.01