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Each NF-AT isoform undergoes nuclear translocation at specific stages of muscle differentiation
| NF-AT isoform | Stage of myogenesis
|
||
|---|---|---|---|
| Myoblastsa | Myotubes (nascent)b | Myotubes (mature)c | |
| c | (−)d | (+)e | (+) |
| Nuclear selectivity | Nuclear selectivity | ||
| p | (−) | (+) | (−) |
| All nuclei | |||
| 4/x/c3 | (+) | (−) | (−) |
80–90% confluent.
24 h in FM.
75–80 h in FM.
(−) indicates lack of calcium-dependent nuclear translocation.
(+) indicates occurrence of calcium-dependent nuclear translocation.
