Table 1.
Effect of inhibitors on HO activity.
Condition | HO Activity |
---|---|
SW | 1.02 ± 0.03 |
TBB 3 μM | 1.05 ± 0.07 |
TBB 10 μM | 1.02 ± 0.05 |
DMAT 10 μM | 1.01 ± 0.08 |
DRB 30 μM | 0.94 ± 0.09 |
GF109203X 5 μM | 0.96 ± 0.03 |
LY294002 40 μM | 1.11 ± 0.09 |
Wortmannin 1 μM | 1.00 ± 0.03 |
Mean HO activity (nmol CO/mg protein/h ± SEM, n = 5-31/condition) in cultures subjected to medium exchange (sham-wash, SW) only or treated for 30 minutes with indicated concentrations of TBB, DMAT, DRB, GF109203X, LY294002 and Wortmannin.