Table 2.
Effect of deletion of RPD3, HDA1, and SIR3 on HMR silencing
| Strain (all hmr::TRP1) | No. of cultures | Frequency of Trp+ colonies (mean ± SD) | Relative frequency |
|---|---|---|---|
| DY2126 (control) | 8 | 5.19 ± 2.74 × 10−6 | 1.00 |
| YSK694 (hda1Δ) | 8 | 6.12 ± 3.97 × 10−6 | 1.18 |
| YSK696 (rpd3Δ) | 11 | 2.08 ± 1.40 × 10−6* | 0.40 |
| YSK726 (sir3Δ) | 9 | 1.03 ± 0.08 | 1.98 × 105 |
| YSK730 (hda1Δ sir3Δ) | 9 | 0.98 ± 0.08 | 1.89 × 105 |
| YSK728 (rpd3Δ sir3Δ) | 12 | 0.92 ± 0.08** | 1.77 × 105 |
*
P < 0.05 compared with the control.
**
P < 0.01 compared with the sir3Δ strain.