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. Author manuscript; available in PMC: 2008 Oct 1.
Published in final edited form as: Biochemistry. 2005 Dec 6;44(48):15774–15786. doi: 10.1021/bi0515974

Table 1.

Activities of human NDK1 mutants

Protein Exonuclease activity NDPK activity
WT ++++a ++++b
E5A − +++
E5Q ++ +++
K12Q + −
F33A + +
D54A − +++
H118F ++ −
D121A − ++
E129A − −
E129Q − −
a

as determined from Fig. 4B.

b

as determined from Fig. 4C.