Figure 1.

Rho family members induce changes in cell shape and actin cytoskeleton in primary QMb. Immunofluorescence micrographs of BODIPY phallacidin–labeled QMb in GM, transiently expressing myc epitope–tagged Rac1L61 (A), Rac1L61C40 (B), Rac1L61A37 (C), Cdc42L61 (D), or RhoAV14 (E), or β-galactosidase (F) used as control. Cells expressing the various transfected constructs were identified by immunolabeling for the myc epitope or β-galactosidase (data not shown); representative cells positive for expression of the myc epitope (A–E) and β-galactosidase (F) are shown. Bar, 10 μm.