Table 2.
Nocturnal Sleep Respiratory Variables of Patients with Prader-Willi Syndrome and Control Subjects
| Variable | Patients (n = 18) | Controls (n = 35) | p Value |
|---|---|---|---|
| RDI, events/h | |||
| NREM | 4.6 (2.6–24.6) | 8.0 (3.0–33.0) | NS |
| REM | 39.2 (23.5) | 22.6 (25.1) | 0.02 |
| Total | 11.3 (5.8–29.5) | 12.0 (4.0.–33.0) | NS |
| Lowest Sao2 %* | 77.0 (67.0-86.5) | 88.0 (81.0-90.0) | 0.005 |
| Percentage of time spent at an Sao2 less than | |||
| 90% | 1.6 (0–46.0) | 0 (0–4.0) | NS |
| 80%* | 0.17 (0-.70) | 0 (0–0) | 0.013 |
| Arousal Index | 23.6 (2.4) | 28.5 (35.9) | NS |
| Longest apnea, sec | 31.8 (24.7) | 21.6 (23.4) | NS |
| Longest hypopnea, sec | 69.9 (45.5) | 52.5 (25.2) | NS |
| Mean nocturnal Sao2, % | 94.6 (2.4) | 95.5 (2.7) | NS |
Data are presented as mean (SD) except those denoted with an asterisk, which are expressed as median (25th–75th percentile). NREM refers to non-rapid eye movement; REM, rapid eye movement; Sao2, oxygen saturation.