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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Chem Res Toxicol. 2007 Dec 4;21(1):160–171. doi: 10.1021/tx7002068

Figure 2.

Figure 2

Total POB-DNA adduct levels in the lungs of rats treated with NNK (closed diamonds), (S)-NNAL (open squares) or (R)-NNAL (closed squares). Rats were treated with 10 ppm of each compound added to their drinking water and were killed at the time intervals shown. Individual POB-DNA adducts were analyzed by LC-ESI-MS/MS-SRM as described (28).