Figure 1.
Effect of TA on uveal melanoma cell proliferation. Cells were treated with four different suspensions: Park Memorial Institute/Dulbecco’s Modified Eagle Medium (RPMI/DMEM; control), RPMI/DMEM with methanol (second control), 10 mM TA suspension, or 100 mM TA suspension. Cell proliferation was determined by a WST-1 assay (absorbance (OD) and the mean±SD is provided for each time point (n=8)). No substantial difference was seen in proliferation of uveal melanoma cell lines between TA treatment and control (cell line 92.1 (p=0.755), OCM-1 (p=0.844), and Mel285 (p=0.487)). Abbreviations: OD is optical density; TA is triamcinolone acetonide; CO is control.