Figure 3.
Multipoint linkage analyses for SWE on chromosome 13. (a) Multipoint VC LOD scores (solid line), MCMC log IR (dashed line) and parametric LOD scores (alternating dashes and dots) are shown for the pericentromeric half of the chromosome. A dotted line marks the score expected in the absence of linkage (LOD score = 0, IR = 1). Four-point parametric LOD scores were calculated using segregation model RL1 (Table I) and the three markers indicated by arrowheads. (b) Multipoint MCMC parametric LOD scores for SWE, based on model RL1, and incorporating all available chromosome 13 markers.