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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: Cancer Res. 2008 Sep 15;68(18):7283–7292. doi: 10.1158/0008-5472.CAN-07-6246

Figure 6.

Figure 6

Immunohistochemistry p27 and Hematoxylin and Eosin (H & E) staining assays using mouse tumor samples. Tumors were collected after 21-day treatment (see Fig. 5 legend), and the prepared tissue slides were used for immunostaining with p27 antibody (A), and H & E staining assays (B). Stronger or/and more p27 positive cells (A), more apoptotic-condensed nuclei (Apo with arrow), and more necrotic tumor cells (Nec with arrow) were found in tumor tissue from mice treated with curcumin. Only few apoptotic cells and much more non-apoptotic cells (Non-apo with arrow) were found in tumor tissue from mice treated with solvent. Magnifications are 100X and 400X as indicated.