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Effect of the SFK inhibitor AP23994 on Lyn kinase activity and cell proliferation. A, TC71 cells were treated with 0, 0.5, 1, or 2 nmol/L AP23994 for 1 h. Cell lysates were collected and assayed for Lyn kinase. B, TC71 cells were treated with various doses of AP23994 or DMSO for 48 h and then assayed by MTT.
