Figure 1.

Investigating context-dependency. Point-wise comparison at a given genome location (the box underlines the location n+2) of probability profiles of a feature X obtained in condition B and under various additional prescriptions C_i (i = 1, 2, 3) with the joint profile constructed from the pooled data. We have denoted in short $P_n^{(i)}=P_n^{(X|B,C_i)}$ and $P_{P_n}^{(i)}=P_{P_n}^{(X|B,C_i)}$ the 'probabilities of probability', i.e. the functional distributions describing the estimated variability of the distributions $P_n^{(i)}$. The comparison aims at determining whether the conditions C_i provide additional information on X and decrease its indeterminacy or whether they can be ignored and the analysis performed on the pooled data. Essential conditions define the 'context' of the feature X.