Table 3.

Symptoms and clinical signs

Drug Group	Quinine				Atovaquone-proguanil				Artemether-lumefantrine
n =	30	30	30	23	30	30	30	26	30	30	30	28
day	0	7	28	90	0	7	28	90	0	7	28	90
Hearing Problem	0	9	1	0	0	1	0	1	1	2	1	0
Tinnitus	2	8	3	0	4	6	1	1	6	4	2	0
Vertigo	6	0	1	0	8	1	0	0	4	3	1	0
Imbalance	1	0	0	0	0	0	0	0	0	0	0	0
Spontaneous nystagmus	0	0	0	0	0	0	0	0	0	0	0	0
Provoked nystagmus	0	0	0	0	0	0	0	0	0	0	0	0
Pathologic head rotation test	1	0	0	0	0	0	0	0	1	0	0	0
Impaired coordination	0	0	0	0	0	0	0	0	0	0	0	0
Fever	24	0	5	2	23	2	3	1	26	0	1	2
Shivering	23	0	1	2	26	4	3	1	21	1	1	1
Headache	30	5	5	2	30	10	6	3	30	7	4	2
Nausea	21	1	2	0	17	1	1	0	22	0	0	4
Diarrhea	4	0	0	0	2	1	1	0	3	0	0	0
Vomiting	1	0	0	0	1	0	0	0	1	0	0	0
Anorexia	2	0	1	0	3	0	0	0	0	0	0	0
Abdominal pain	1	0	0	0	0	0	0	0	1	0	0	0
Arthralgia	3	0	0	0	3	0	0	0	1	0	0	0
Myalgia	1	0	0	0	0	0	0	0	0	0	0	0
Chest pain	0	0	0	0	0	1	0	0	0	0	0	0
Cough	0	1	0	0	0	1	0	0	0	0	0	0