Table 5. Geographical differences in Pvama1 and Pfama1 sequences across all domains.
P. vivax ama1 pairwise FST estimates | Venezuela (73) 1 | P. falciparum ama1 pairwise FST estimates | Venezuela (30) 2 | ||
Sri Lanka (23) 2 | Nigeria (50) 4 | ||||
Whole | 0.074 | Whole | 0.258 | ||
DI | 0.120 | DI | 0.265 | ||
DII | 0.185 | DII | 0.192 | ||
DIII | 0.322 | Sri Lanka | DIII | 0.240 | Nigeria |
India 3 | Thailand (51) 5 | ||||
Whole (33) | 0.091 | 0.048 | Whole | 0.273 | 0.019 |
DI (33) | 0.109 | 0.058 | DI | 0.286 | 0.039 |
DII (34) | 0.034 | 0.223 | DII | 0.344 | 0.086 |
DIII (34) | 0.349 | −0.035 | DIII | 0.276 | 0.056 |
Pairwise FST values between Venezuelan sequences and other sites are highlighted. Sample sizes are in parenthesis. 1 = all Venezuela Pvama1data from both 1996 and 1997; 2 = all Venezuela Pfama1 data from 1996 only; 2 = [15]; 3 = [35] one sequence was ignored in the whole gene and DI analysis as it was not full length; 4 = [19]; 5 = [18]. Significant difference (P<0.05) indicated by bold text. Slightly negative numbers, indicated by italics, are biologically meaningless and are equivalent to FST = 0.000.