Figure 3. Specific antibody titers in mice to P. yoelii and P. berghei sporozoites following a prime-boost vaccination regimen with CAS or RAS.
Sera from animals immunized with P. yoelii CAS or RAS was obtained and titers were determined by immunofluorescence using whole sporozoites from P. yoelii (A) or sera from animals immunized with P. berghei was used to determine titers and P. berghei sporozoites (B). Each circle represents data from one mouse. Black circles represent data where sporozoites were florescent, while open circles represent the lowest dilution of serum that did not produce florescent sporozoites. The experiment was completed in triplicate at each concentration for sera from each animal.